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1996-03-09
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Document 0112
DOCN M9650112
TI Vertical transmission of HIV-1 infection. Diagnosis and prevention.
DT 9605
AU Ugen KE; Department of Medical Microbiology and Immunology, University
of; South Florida College of Medicine, USA.
SO J Fla Med Assoc. 1995 Dec;82(12):825-6. Unique Identifier : AIDSLINE
MED/96156899
AB With an increase in the number of women of childbearing age being
infected with HIV-1, the incidence of pediatric AIDS is rising
precipitously. Therefore, it is necessary to identify the risks and the
potential preventive methods that may be effective in decreasing the
transmission from mother to child, i.e., vertical transmission.
Administration of zidovudine has been demonstrated to significantly
lower the rate of vertical transmission. Passive and active vaccination
may also be useful in diminishing the transmission rate. Likewise,
methods which provide a rapid and predictive measurement of the
likelihood of vertical transmission, such as qualitative and
quantitative differences in anti-HIV-1 maternal antibodies between
transmitters and nontransmitters, have potential clinical utility.
DE Adolescence Adult Antiviral Agents/THERAPEUTIC USE *Disease
Transmission, Vertical/PREVENTION & CONTROL Female Human HIV
Antibodies/ANALYSIS HIV Infections/CONGENITAL/DIAGNOSIS/PREVENTION &
CONTROL/ *TRANSMISSION *HIV-1/IMMUNOLOGY Incidence Infant, Newborn
Risk Factors Vaccination Zidovudine/THERAPEUTIC USE JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).